The Clinical Application of Recombinant Human Bone Morphogenetic Protein 7 for Reconstruction of Alveolar Cleft: 10 Years' Follow-Up
نویسندگان
چکیده
منابع مشابه
Reconstruction of alveolar cleft with allogenous bone graft: Clinical considerations.
INTRODUCTION Secondary bone grafting consists in a routine procedure on the treatment of patients with alveolar cleft. Usually, it is performed by the end of the mixed dentition, when the permanent canine is erupting, with autogenous cancellous bone from the iliac crest. OBJECTIVE The present article discusses the alternative of autogenous bone grafting with allogeneic bone, obtained from hum...
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introduction : surgical repair of cleft palate with a bony bridge may offer some distinct advantages including a lower rate of fistula formation. the goal of this study was to evaluate the feasibility of surgically inducing cleft palate and reconstruction of the cleft with the use of bone morphogenetic protein-2 (bmp-2) in sheep. materials and methods : in the control group (two sheep), the cle...
متن کاملOptimization of extracellular production of recombinant human bone morphogenetic protein-7 (rhBMP-7) with Bacillus subtilis.
Extracellular production of recombinant human bone morphogenetic protein-7 (rhBMP-7) was carried out through the fermentation of Bacillus subtilis. Three significant fermentation conditions and medium components were selected and optimized to enhance the rhBMP-7 production by using the response surface methodology (RSM). The optimum values of the three variables for the maximum extracellular pr...
متن کاملUse of recombinant human bone morphogenetic protein 2 for mandible reconstruction.
BACKGROUND Microvascular osseous free tissue transfer is the standard of care for reconstructing significant mandibulectomy defects; however, this procedure can carry a significant rate of morbidity. OBJECTIVES To describe the use of recombinant human bone morphogenetic protein 2 (rhBMP-2) as an option for segmental or near-complete rim mandibulectomy defects in a select group of patients, pr...
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Introduction: The aim of this study was to evaluate the effect of platelet-rich fibrin (PRF) on the quality and quantity of bone formation in unilateral maxillary alveolar cleft reconstruction using cone beam computed tomography. Materials and Methods: This study was conducted on 10 non-syndromic patients with unilateral cleft lip and palate within the age group of 9-12 years. The study popul...
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ژورنال
عنوان ژورنال: Journal of Oral and Maxillofacial Surgery
سال: 2019
ISSN: 0278-2391
DOI: 10.1016/j.joms.2018.08.031